| Athlete | 100 2024 | 100 2025 | Difference |
| Landon Walker - Kelly Walsh High School | 11.55 | 11.12 | 0.43 |
| Jacob Backman - Natrona County High School | 11.6 | 11.24 | 0.36 |
| Rudy Green - Sheridan High School | 11.58 | 11.26 | 0.32 |
| Logan Borden - Natrona County High School | 11.03 | 10.81 | 0.22 |
| Johnson Cedric - Cheyenne East High School | 11.26 | 11.06 | 0.2 |
| Christian Lopez-Ramirez - Thunder Basin High School | 11.51 | 11.33 | 0.18 |
| Brady Dona - Glenrock High School | 11.53 | 11.46 | 0.07 |
| Gage Brooks - Natrona County High School | 11.45 | 11.41 | 0.04 |
| Taven Young - Thunder Basin High School | 11.15 | 11.15 | 0 |
| Flynn Arnold - Laramie High School | 11.28 | 11.28 | 0 |
| Gavin Gilbertz - Sheridan High School | 11.48 | 11.53 | -0.05 |
| Zander Kumm - Thunder Basin High School | 11.28 | 11.38 | -0.1 |
| Chance Morris - Sheridan High School | 10.67 | 10.8 | -0.13 |
| Dalton Marincic - Rock Springs High School | 11.33 | 11.52 | -0.19 |
| Jackson Reed - Laramie High School | 11.09 | 11.29 | -0.2 |
| Josh Galbert - Cheyenne Central High School | 11.07 | 11.3 | -0.23 |
| Douglas Anderson - S... |